Progesterone and Fertility

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Fertility & Progesterone

Progesterone is recognized as a vital female hormone central to successful conception and a healthy pregnancy. The word "progesterone" is itself etymologically related to the Latin root gestare - meaning to bear or carry - suggesting the importance of this hormone in creating a fertile environment for conception and the continuing development of the embryo. (Many women report that FertilAid for Women has helped normalize their progesterone levels. Additionally, many women indicate that external adminstration of a natural progesterone cream such as FertileBalance can be beneficial.)

In short, progesterone is a female sex hormone that is secreted by the corpus luteum to prepare the endometrium for implantation of the fertilized egg. Following implantation off the egg, the developing placenta signals the body to produce progesterone and prevent rejection of the developing embryo or fetus. Without this continuuing progesterone production, the endometrium would shed and menstruation would ensue. Therefore, progesterone plays a significant role in reproduction. Thus, progesterone...

  • Helps create a fertile, warm environment in the womb and promotes the survival of the fertilized egg through healthy implantation.
  • Strengthens and maintains the secretory endometrium which sustains the embryo throughout pregnancy.
  • Prevents the premature shedding of the secretory endometrium (menstruation).

As progesterone forestalls the shedding of the endometrium (where embryo implantation occurs), low progesterone levels - or a significant drop in progesterone levels - during the first few weeks of pregnancy may correspond with miscarriage.

Here, progesterone plays a 'secretory’ role in the reproductive organs. It stimulates changes in the uterus and supports pregnancy by increasing blood vessel and tissue development in the endometrium.

Progesterone, Fertility, and Reproduction

During a woman's cycle, progesterone levels rise rapidly at ovulation to provide a fertile environment for the fertilized egg. Here, progesterone is also responsible for the increase in body temperature at ovulation that lasts through most of the luteal phase. Beginning with ovulation, the corpus luteum produces progesterone for several days (and the concomitant temperature increase is in most cases easily measurable through methods of BBT/fertility charting).

If fertilization and implantation take place, the placenta takes over the role signalling progesterone production and in further maintaining a supportive environment for embryonic and fetal development. If fertilization does not occur, progesterone levels fall dramatically (usually after 10-12 days) triggering the shedding of the secretory endometrium (menses).

Because progesterone is essential in preventing the shedding of the secretory endometrium, a significant drop in progesterone levels during the first 10 - 12 weeks of pregnancy may result in a miscarriage.

Addressing the Issue of Low Progesterone Levels

Low progesterone can be detected by a blood test after ovulation or by charting fertility. Another sign of low progesterone is a shortened luteal phase that lasts less than 10 days.

There are several things you can do to boost deficient progesterone levels. Clearly, visiting a doctor to discuss the nuances of a particular issue may be the best first option. However, a fertility supplement, like FertilAid for Women, may help to bring progesterone levels into an ideal range for achieving pregnancy.

Women with a history of miscarriage can also use natural progesterone cream as soon as they know they have ovulated, to supplement their own progesterone; however, natural progesterone creams should not be used until ovulation takes place. Consult your physician for more information on the benefits of progesterone and uses/applications.

Other Applications of Progesterone

Progesterone has many other functions, among them protecting against fibrocysts, helping the body use fat for energy, and helping normalize blood clotting and blood sugar levels. Today, many health professionals claim that the symptoms associated with PMS and menopause are due not so much to estrogen, but to a deficiency of progesterone and an overabundance of estrogen. It is believed that progesterone balances estrogen and that an overproduction of estrogen can lead to health problems. However, consult your physician if you have any questions about using natural progesterone creams.

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> Anovulation
> Short Cylces Why are short menstrual cycles a possible TTC issue?


Hi all,
I am 23, and new to this site. I have pcos and endometriosis which i had treated 3 yrs ago but has come back. I have been tryin for baby with my partner for 18months and I found out that my Progesterone was really low and that i havent been ovulating for i dont no how long. Sadly I have been on clomid 50mg for the last 3 months, for the first 2 months the doc said that it had worked but my 3rd wen the hospital tested me they said my levels are 2.4. I am gutted.... I have lost weight, give up smoking and started to get exercise wen we started trying for a baby, and i dont feel like i am getting anywhere....I am worried about goin onto the 100gm clomid coz it effects the pcos and i dont want to make anything worse..All I want is to be able to have a baby, its all i have ever wanted....Is there any advise any could give me...

have PCOS, took clomid 50mg and did not progesterone was .03, then started taking clomid 100 mg. this will be 100mg for the 3rd month.....had a chemical pregnancy last month, and my progesterone was 12, this month it was 9..... why did it go down? and is this normal?? please any help would be great!!!

On 11/3 took a prego test it faintly came up positive told my partner n bc I have a history of low progesterone n 1 miscarriage we made a dr appt for 11/5 (earliest they could take me) we picked up my last dr records showing low progesterone level, however it was dated in 2008 so at the appt my dr dismissed it and said I'm probably less than 4 weeks. They took my blood (hcg, blood type, progesterone) and ultra sound which only showed no sac, thickening uterus wall, which tech said was all normal and perhaps indicated less than 4 weeks. Now today I am bleeding almost as if it's my period. Guess I am miscarrying. I just wonder why the dr could not just treat me with low progesterone and possibly prevent this from happening. Tomorrow they are suppose to call me to tell me if I have low progestrone and advise if I need treatment. Guess maybe I should have pushed harder on Friday but it felt like they were I guess doing what they could. Sad now I'm 33 n this is my second miscarriage in 6 years and no children.

the first day you have your period is day 1, you start your clomid on day 5-9, try to conceive on days 12-20 (every other day), then get your progesterone drawn on day 21 to see if you ovulated. you should take a pregnancy test on day 35 if you ovulated and didnt have a period. best of luck to you all. i have PCOS and have been trying to conceive for a year....first few months on clomid i still did not ovulate (highest level was .03) then i had a chemical pregnancy, now we are still trying but no luck yet..... last time my progesterone had dropped from 12 to 9 is that normal?

Hi Everyone,

This is my first time being pregnant. I am 5weeks along right now. I had 3 blood tests down so far. On the most recent blood test my doctor told me my hcg was rising, but my progesterone had dropped from 12 to , 9 and then 7. I am really worried now. I went in for an ultra sound and they a saw a sac but no fetal pole yet. The nurse said I am at where should be at 5 weeks, but I just have to wait and see. My doctor prescribed 200 mg of prometrium once a day. Am I miscarrying. Any Answers Would help thank you.

hi all,
would like to say there is hope for you all, after me and my partner had been trying for 4 years to have a baby and still no pregnancy we then decided to get some tests done, we found out after lots of blood tests that i had low progesterone but didn't stop us still trying to have a baby so the next 2 years we carried on trying but still with no luck so decided to give up. the next think i know i was feeling really odd and not myself so 2 weeks later decided to take a pregnancy test only to find a big fat positive on the result bar, i was so pleased but ever so scared but now im 14 weeks gone and had first scan im over the moon with are little bundle of joy growing inside my belly, i just wonted to post on hear and say there is hope for everyone and it will happen love and kisses to you all and good luck xxxx

Hi Guys pls i am new to this site i have low blood sugar and i have been coping with that but i started having miscarriage and had a test done for progesterone i found out that it was very low 3.3 so please i am very confuse i need all the help and assitance i could get to get it sorted i don't know what caused the low sugar and low progesterone please help me i am very worried thanks

We have been trying for a baby for over 6 months. 2 Months ago i started using ovulation tests to try and pin point the best times to start trying but noticed that they never picked up a LH level. I have just had my blood test results back and have found out i do ovulate but me hormone levels are below average - results 27.7, should be over 30. They want to carry out another test next month on day 21 again. What can be done to help increse this? Is this level really low? I am scared!

I have child and have been trying for another for 18month had no trouble conceiving first time round but am now I have had blood tests which have come back ok but was ask to have progesterone bloods test done which has come back low. So need to have it done again my period was early would that have anything to do why it was low?? Also when I have worked out day 21 it's on a weekend the doctor said I need to wait till next month to have it done again does anyone have any ideas so I don't have to wait?? My cycle was 26 days do I still count 21 days to have the test again??

when am i supossed to take the 21 day progesterone test

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