Clomid: How it Works and What to Expect

The service having id "google_buzz" is missing, reactivate its module or save again the list of services.

Is Clomid the Right Fertility Medication for Me? Clomid, Infertility and Ovulation Induction


Clomid (clomiphene, clomiphene citrate) is among the most well-know and frequently prescribed of all fertility drugs. Clomid is taken orally and is considered a "first line" prescription fertility drug for dealing with infertility issues. Clomid is so widely prescribed that you may even find a "Clomid Club" on many preconception forums and communities. Clomid is used predominately for inducing ovulation in women with ovulatory disorders like anovulation, PCOS, and other infertility symptoms.

Clomid works by impacting hormonal production, by influencing the "fertility hormones" (estrogen, FSH, and LH) that precipitate ovulation. Like many prescription medications, Clomid works by "tricking the brain" into believing that estrogen levels in the body are low. This in turn encourages the brain to send signals to release more Gonadotropin Releasing Hormone (GnRH), which causes the pituitary gland to produce more FSH (follicle stimulating hormone) and LH (luteinizing hormone). LH is the hormone that facilitates ovulation (the release of the egg), and it's also the hormone used as the marker in urine ovulation testing.

Sounds complicated? In effect, clomid precipitates, through these various hormonal mechanisms, increased production of LH and FSH, which in turn foster a mature ovarian follicle and the release of the ovum. This is called ovulation induction. In more clinical terms, Dr. G. Berger notes: "Structurally like estrogen, clomiphene binds to the sites in the brain where estrogen normally attaches, called estrogen receptors. Once these receptor sites are filled up with clomiphene, they can't bind with natural estrogen circulating in the blood and they are fooled into thinking that the amount of estrogen in the blood is too low. In response, the hypothalamus releases more GnRH, causing the pituitary to pump out more FSH, which then causes a follicle to grow to produce more estrogen and start maturing an egg to prepare for ovulation".

Clomid is taken orally for about five days near the beginning of the cycle. Dosage and "start dates" will be indicated by the prescribing doctor. Once ovulation commences, most pregnancies occur in the first 6 cycles of treatment. While clomid has a high rate of success in inducing ovulation, it cannot guarantee pregnancy. Note: if you test too early for ovulation in your cycle with a urine ovulation test (lh), you may receive a false positive on an ovulation test when using clomid.

Fertility Supplements and Clomid: Currently, there are a number of herbal-nutritional supplements on the market containing vitex (chasteberry, vitex agnus castus). These products may be viewed as an herbal infertility therapy, and products like FertilAid and FertilityBlend are based on impressive clinical studies indicating that fertility can be improved with fertility supplementation. However, both of these manufacturers indicate that clomid should not be used in conjunction with vitex (or herbal infertility products in general). Fertility supplements like Fertility Blend and FertilAid are non-prescription. While on clomid, women are still encouraged to take a prenatal supplement with folic acid.

Well-known side effects of clomid include - you guessed it - multiple births (aka twins, triplets...). For women using clomid, twins may occur in 5% of births. Triplets are much less frequent. Although there has been some discussion linking prescription infertility treatments like clomid to ovarian cancer, evidence seems to point now to other causes, even infertility itself as a cause of some cancers. There is no evidence that clomid causes an increase in congenital abnormalities or birth defects in children.

Clomiphene and Clomid Abuse. While clomid cannnot be "abused" in any traditional sense, it can be prescribed (or rather over-prescribed) for infertility issues before a fertility workup has been performed, or before there is even any sign of ovulatory disorder, anovulation, luteal phase defect (LPD), PCOS, etc. Proper screening is essential prior to prescription. Given that male fertility issues constitute nearly 30% of infertility cases, a thorough evaluation and/or fertility workup should be performed on the woman to verify that ovulation induction via clomid is indeed required. For women without ovulatory/ovulation issues or infertility symptoms, clomid use may actually interfere with conception. Before accepting a clomid prescription, ensure that your doctor has performed the requisite infertility workup and/or has correctly identified a fertility issue or ovulatory disorder.

Women with liver disease should not use clomid. Clomid should not be given to patients with ovarian cysts, since they may grow larger. It should not be taken by a patient who may be pregnant, although there is no proof of fetal problems or complications.

> Back to Infertility and Fertility Medications
> What you can learn from your bbt chart.

Comments

This is such a great resource that you are providing and you give it away for free. I love seeing websites that understand the value of providing a quality resource for free. It is the old what goes around comes around routine.

When I initially commented I appear to have clicked on the
-Notify me when new comments are added- checkbox and from now on each time
a comment is added I receive 4 emails with the exact same comment.
Is there a way you are able to remove me from that service?
Thanks!

Greetings from Colorado! I'm bored to death at
work so I decided to check out your site on my iphone
during lunch break. I enjoy the knowledge you present
here and can't wait to take a look when I get home. I'm shocked at
how quick your blog loaded on my mobile .. I'm not even using WIFI, just 3G ..
Anyhow, amazing blog!

What's up it's me, I am also visiting this website on a regular basis,
this website is genuinely nice and the people are truly sharing good thoughts.

This is actually the kind of information I have been trying to find. Thank you for writing this information.

Thanks for any other informative web site.
The place else may I get that type of information written in such an ideal method?I've a mission that I'm just
now runnning on, and I've been at the look out for such info.

wonderful publish, very informative. I'm wondering why the
opposite specialists of this sector do not notice this.

You should continue your writing. I am sure,
you have a great readers' base already!

Feel free too visit my blog - [url=https://www.youtube.com/watch?v=rPrj0woeVio]google website ranking list[/url]

My brother suggested I mght like this blog. He used to be totally
right. Thiis put up truly made my day. You cann't imagine simply how a lot time I had spent
for this information! Thank you!

Hi tɦere, tɦiѕ weekend is nice in favor off
me, for the reason that thijs point in time i am гeading this enormouss educational piece off writing here at
my house.

I know this site presents quality dependent posts and additional material, is
there any other web page which gives these kinds of information in quality?

Post new comment

The content of this field is kept private and will not be shown publicly.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Allowed HTML tags: <a> <em> <strong> <cite> <code> <ul> <ol> <li> <dl> <dt> <dd>
  • Lines and paragraphs break automatically.
  • Textual smileys will be replaced with graphical ones.

More information about formatting options

Ovulation Calculator

Format: 9/22/2014
Increase your chances of getting pregnant! Our Ovulation Calculator will help you predict when you ovulate - your prime time for becoming pregnant.

OvaCue Fertility Monitor at Early-Pregnancy-Tests.com

Our Blog

 
By TTC veteran and mother of two, Elizabeth Andrews.